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Archive for the ‘Multiple Sclerosis’ Category

PostHeaderIcon Pathophysiology Of Multiple Sclerosis

What is multiple sclerosis?

Multiple sclerosis is a chronic disease that is non-contagious. It predominantly affects the brain and the spinal cord. It is mainly characterized by a wide variety of neurological symptoms that are caused by the demyelization of the neurons. Moreover, it is an autoimmune disease in which the body’s very own immune system attacks the central nervous system’s cells and underlying tissues.

What causes it?

The ultimate cause of multiple sclerosis remains unknown. This means that multiple sclerosis is an idiopathic disease. According to scientific research, some viral infections or other environmental factors related to childhood are able to trigger the abnormal reactions associated with the immune system.

On a molecular level, a structural similarity can be discovered between an infectious agent that is not identified and some components of the central nervous system. This similarity causes confusion in the immune system’s fighter cells when the body matures later as the body ages. This whole process is termed as molecular mimicry. And since there is no such thing as a multiple sclerosis virus, it can be declared that the disease is not at all contagious.

Where the WBC come in

Most of this information comes straight from the Multiple Sclerosis pros. Careful reading to the end virtually guarantees that you’ll know what they know.

The body’s white blood cells, more commonly referred to as WBC, have a special subset of cells termed as T cells. These T cells are key players in the development of multiple sclerosis. Normally, these lymphocytes have the ability to differentiate substances or components that belong to the body from those that are foreign. Whenever a foreign body is recognized, the whole immune system is put on alert and the body’s fighter cells attack the foreign body to maintain homeostasis within the body.

However, since multiple sclerosis is an autoimmune disease, it tends to attack itself. The T cells recognize the healthy parts of the central nervous system as something harmful and foreign and attack them as if it is a response aimed at a virus or bacteria.

The T cells attack predominantly attack the myelin which insulates the axons of the nerve cells. This fatty substance is very important, especially when it comes to proper nerve conduction.

About the BBB

There is a normal barrier that goes between the blood and the brain that medical professionals have coined as the blood-brain barrier or the BBB. This BBB is made up of endothelial cells that line the blood vessel walls.

It is during multiple sclerosis that the BBB breaks down and the auto-reactive T cells enter the BBB, when they are clearly not supposed to. After crossing the BBB, the T cells then trigger an inflammatory response that is further mediated by other immune cells namely the cytokines and antibodies. After further inflammatory responses, there is a much bigger opening of the BBB and a wide variety of symptoms are produced.

Moving on, the macrophages are alerted, there is an activation of the MMPs, including other proteases. In short, this all leads to the destruction of the myelin, a process that is termed as demyelization.

Hopefully the sections above have contributed to your understanding of Multiple Sclerosis. Share your new understanding about Multiple Sclerosis with others. They’ll thank you for it.

About the Author
By Kenneth Allan Crosby jr,feel free to visit his top ranked recycling site: recycling, tips, history

PostHeaderIcon Not Everyone With Multiple Sclerosis Is On Treatment

Why treatment is considered a must

Having multiple sclerosis types such as relapsing – remitting, progressive – relapsing and secondary – progressive means that a doctor must be consulted as quickly as possible since taking or undergoing of disease –modifying treatment is a must at this point.

Even though there are no exacerbations, or painful and unmanageable symptoms or a present hate of needles, a physician must be consulted right away. Despite the fact that MS-related drugs have some side effects and are oftentimes inconvenient, they are still very helpful in reducing the risk for relapses and can even decrease the severity of disability for most.

However, some of those who are diagnosed with multiple sclerosis choose not to undergo treatment. In a certain study that focused on the patterns of prescription of all of the MS drugs that are known to modify the disease process and its progression, ninety-two percent visit doctors while sixty-percent opt not to have therapy.

Common assumptions

There are some costly fees associated with private insurance that seem to deter them from having therapy.

There are those with only mild symptoms, more likely in the first stages of the disorder, and choose to postpone treatment. It seems like they would want to see first what happens if they do not accept treatment. In other cases, the doctors are the ones who advise their patients to delay having therapy, especially if the symptoms are only mild in severity.

In some cases, both the patient and the physician want to see first the results of a new medication.

Most of this information comes straight from the Multiple Sclerosis pros. Careful reading to the end virtually guarantees that you’ll know what they know.

Most of the time, those with MS just do not take treatment simply because they do not fully understand the pros and the cons of having or not having it. Some patients are also told by their corresponding doctors not to have treatment because they do not fit for the criteria for taking the certain treatment modality.

The many differences in the patient-physician communication can limit the uptake of the treatment.

Some doctors believe that the suitability of the medications can halt them from giving drug prescriptions. What the doctors know regarding internal organizational policies and rules about using drugs related to multiple sclerosis therapy may also halt them from openly prescribing such medications.

Dislike of needles

People diagnosed with multiple sclerosis are usually scared of needles. Actually, they are probably afraid of needles even before their multiple sclerosis onsets. It is a known fact that this part is definitely no fun.

None of the drugs for treating multiple sclerosis can be taken per orem, which means orally. This means that they have no other choice but to endure an intramuscular, intravenous or a subcutaneous form of the drug.

The drug’s side effects

In most cases, people just hate taking drugs. This is usually because they are afraid of the side effects that may occur. This fear is explainable and understandable but emphasis should still be given to older MS drugs such as Copaxone, Avonex, Rebif and Betaseron since they are all safe to take.

When in doubt about a certain drug, neurologists can be consulted since they are knowledgeable on which treatment methods fit a certain type of lifestyle. Also, they can provide some tips regarding the management of side effects.

Hopefully the sections above have contributed to your understanding of Multiple Sclerosis. Share your new understanding about Multiple Sclerosis with others. They’ll thank you for it.

About the Author
By Anders Eriksson, now offering the best guide on movie downloads over at free movie downloads

PostHeaderIcon Multiple Sclerosis Differential Diagnoses And Workups

Have you ever wondered what exactly is up with Multiple Sclerosis? This informative report can give you an insight into everything you’ve ever wanted to know about Multiple Sclerosis.

CSF exam

Upon examining the cerebrospinal fluid of those who have been diagnosed with multiple sclerosis, otherwise referred to as MS, electrophoretic patterns can be observed. These patterns are made up of oligoclonal bands that indicate any significant increase in the person’s IgG. In fact, roughly eighty-five percent of MS patients demonstrate this finding.

Usually, the glucose level is within normal range. However, the protein level can be either normal or mildly increased. And the white blood cells range from slightly up to moderately increased but no exceeding five, specifically the mononuclear cells.

The MBP or the myelin basic protein is an important workup in MS. This component of myelin is increased in multiple sclerosis. Still, however, physicians do not recommend using the MBP’s as the marker to indicate the disease process or the progression of multiple sclerosis.

Blood tests

Those with MS must be tested for their B12 and their Folate levels, including their antinuclear antibody, or their ANA titers. Such tests are essential whenever there is evidence of a fast-acting deterioration in the cognition or degeneration of the person’s spinal cord.

Multiple sclerotic people experiencing optic neuritis and spinal cord lesions that are somewhat extensive should go to the laboratory to be tested for NMO or neuromyelitis optica. This test will determine the presence of antibodies of aquaporin 4 flowing within the serum.

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An ESR or an erythrocyte sedimentation rate must also be taken, along with positive titers of a rheumatoid factor. These specific blood tests help in identifying if the disease being experienced by the person is indeed MS or just a vasculitic disease that apes multiple sclerosis.

Imaging studies

An MRI scan of either the head or the spine, with or without gadolinium, must be performed depending on whichever location the lesions are suspected.

Lesions that appear in relation to the onset of multiple sclerosis typically appear looking like T2 hyperintensities located within periventricular areas. These typical lesions have an ovoid shape and usually affect the white matter only. In some cases, several lesions grow from the corpus callosum of the brain.

Whenever the scans indicate lesions from the corpus callosum, this is termed as Dawson fingers. This term came from the work done by James Dawson back in 1916 as a neuropathologic test at the University of Edinburgh. This kind of condition indicates that the cells associated with inflammation have been distributed perivascularly into the veins and the venules of the brain tissues.

Imaging studies can also show any formations of plaque, especially in infratentorial regions. Moreover, the most common infratentorial areas affected by the plaques are the cerebellar peduncles, the pons’ surface and also the white matter part closest to the fourth ventricle.

Once gadolinium is used as the contrast dye, some lesions become luminescent. This result is indicative of an active disease process. Such luminescence means the BBB or the blood-brain barrier has broken down because of a constant subacute process of inflammation, ranging from a few days up to several weeks.

If a combination of both luminescent and non-luminescent lesions is observed, then this would further indicate the chronicity of the disease’s demyelinating process.

About the Author
By Anders Eriksson, proud owner of this top ranked web hosting reseller site: GVO Hosting

PostHeaderIcon Common Human Bacteria Triggers Multiple Sclerosis

The following article presents the very latest information on Multiple Sclerosis. If you have a particular interest in Multiple Sclerosis, then this informative article is required reading.

Up to now, there is ongoing research with regards to the factors that could trigger the onset of multiple sclerosis, more popularly termed as MS. Some findings indicate that there is an ordinary oral bacterium that could complicate this debilitating autoimmune disorder.

More information on multiple sclerosis

Multiple sclerosis is actually a disease wherein the body’s very own immune system attacks the brain, including the spinal cord. This disease affects one in approximately seven hundred people in the U.S. area. Those who have MS display a variety of symptoms such as neurological ones, difficulty in mobility and speech, and muscle weakness.

The common bacteria

The common bacteria, being talked about, are the porphyromas gingivalis, which is very common in human beings. These bacteria produce a very unique form of lipid called phosphorylated dihydroceramides or DHC’s. The DHC enhances the inflammatory response of the person. Also, this lipid is produced in other regions of the body, usually in the gastrointestinal tract.

These bacteria can be detected by identifying first if there is any DNA that specifically responds to this particular strain. This can be done by having a polymerase chain reaction, which is used for characterizing any evidence of DNA that specifically respond to the porphyromas gingivalis.

With this diagnostic tool, the presence of such bacteria can be identified in the oral cavity. This further suggests that early detection, including eradication, pay important roles in prophylaxis for this autoimmune disease.

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Actually, a study was initiated by experts from the University of Connecticut Health Center such as Robert Clark and Frank Nichols. They started with this research in order to determine if such lipids can accentuate the immune-mediated impairment in this specific autoimmune sickness.

According to the findings of this study, the disease’s severity was enhanced whenever there were more these lipids. This concludes that the DHC’s which were phosphorylated from the said bacteria that are usually found in the body of humans can actually trigger, or in some cases, increase, the severity of multiple sclerosis.

Triggering factors

It is already a known fact that during an autoimmune attack, the own immune system attacks self tissues that could either be healthy or damaged. Either way, the immune system’s cells attack them all.

In the case of multiple sclerosis, the cells attack the protective covering of the nerves which is called the myelin. Apart from serving as protection, the myelin also aids in the proper transmission of signals between the brain and the rest of the body.

After proving that phosphorylated DHC’s from common bacteria found in humans can aggravate the process of this particular autoimmune system. Their next goal is to exemplify the effects of such DHC’s on the immune system’s cells. Also, they would like to identify exactly how the DHC’s are deposited in the tissues and exactly which tissues it prefers to be deposited in

They have also determined that phosphorylated DHC’s have a big potential to be the markers of multiple sclerosis’ disease process and also as the new targets when it comes to therapeutic intervention.

About the Author
By Anders Eriksson, proud owner of this top ranked web hosting reseller site: GVO Hosting

PostHeaderIcon Childbirth May Slow Multiple Sclerosis

Have you ever wondered if what you know about Multiple Sclerosis is accurate? Consider the following paragraphs and compare what you know to the latest info on Multiple Sclerosis.

The women who already have at least one child have a thirty-four percent less of the possibility of having a progressive state of multiple sclerosis. According to studies, those women who do not have children yet are more likely to reach a stage of MS where they would need assistance in walking with a brace or a cane.

Having a child before or after the symptoms of multiple sclerosis started to appear is of great help. On the other hand, those women who had children even after the onset of their disease’s symptoms were much better off. Either way, it seems that pregnancy helps in cases of multiple sclerosis.

What the experts say

In fact, according to an expert from the Department of Neurology at the National MS Centrum which is located in Mesbroek, Belgium, named Marie D’hooghe, women who have multiple sclerosis and children tend to have a benign type of MS. This finding is in comparison to those women who have not yet given birth.

Research on multiple sclerosis indicates that eighty-five percent of those who unluckily develop MS initially have a relapsing – remitting type. This means that attacks associated with this particular disease are usually followed by either total or partial recovery. More than fifty percent actually have a progressive state of the disease.

When this happens, the symptoms become much worse and more difficult to handle, and the rest periods where the symptoms disappear for a while become shorter. After some time, the MS process will lead to having a loss of vision, or worse, paralysis.

Women are more at risk than men.

How can you put a limit on learning more? The next section may contain that one little bit of wisdom that changes everything.

Research has it that females are more predisposed to having multiple sclerosis. However, such cases are less severe as compared to the severity of the disease in males.

In the study conduced by the researchers mentioned, three-quarters of the female respondents have already had children. What the researchers did was they monitored the duration needed before the women reached sixth level based on the EDSS or the Expanded Disability Status Scale.

The Expanded Disability Status Scale

The EDSS is a system for rating that is used as a tool by many physicians for determining the severity of the symptoms associated with multiple sclerosis. For instance, first level means the severity is least severe, level ten means death is near. On the sixth level, it means that he or she needs to make use of an assistive device for mobility.

Research findings

For those who have no experience of giving birth usually had an average of thirteen up to fifteen years before finally progressing to the sixth level on the EDSS. On the other hand, those who already have children took some twenty-two up to twenty-three years before reaching that stage.

Moreover, the Director of the biomedical research from the National Multiple Sclerosis Society, Patricia O’Looney, say that there are indeed benefits for female patients who have already had children. Still, however, there is not enough data derived from their demographics to totally come up with some conclusions.

About the Author
By Kenneth Allan Crosby jr,feel free to visit his top ranked recycling site: recycling, tips, history

PostHeaderIcon How To Know If It Is A Multiple Sclerosis Relapse

With multiple sclerosis, relapses are probably the most frustration-filled area of the disease. Apart from the person with complaint having to endure such annoying and painful relapses, that person’s family and physicians are also given a hard time.


Earlier on, many assumed that the returning tingling in the feet, otherwise termed as paresthesia, is an exacerbation. There are some days where this paresthesia is nearly completely gone, and in some days it just prevents the person from ambulating. Aside from this disturbance in the lower extremities, there is also the girdle-band pain that just would not go away.

With these kinds of symptoms, it is best to see a neurologist right away, especially if the symptoms are starting to interfere with normal functioning.

What is a relapse?

Relapse is the term given to an occurrence wherein the signs or symptoms are clinically significant. Such event is usually caused by lesions associated with multiple sclerosis, specifically the ones located inside the brain and spinal cord. Relapses have also been given other terms such as flares, exacerbations and attacks.

What causes a relapse?

The inflammation triggered by an immune response within the body causes the relapses. Since multiple sclerosis is an autoimmune disorder, the immune system attacks its own cells including the healthy ones. In the case of MS, the myelin sheath is attacked.

The more authentic information about Multiple Sclerosis you know, the more likely people are to consider you a Multiple Sclerosis expert. Read on for even more Multiple Sclerosis facts that you can share.

The myelin sheath serves as the protective covering of the nerves. Aside from protection, it also aids in the proper conduction of signals and messages for appropriate communication between the brain and the rest of the body.

With a damaged myelin, a lesion forms and demyelization occurs. This makes the nerves even less effective in transmitting signals properly. The symptoms associated with MS greatly depend on where the lesion is located. For example, if the lesion is located inside the cerebellum, then it will primarily cause incoordination and general imbalance. On the other hand, if the lesion has damaged the optic nerve, then the resulting symptom is a decrease in vision.

What signals a relapse?

Some relapses can be immediately observed. For example, once optic neuritis attacks, vision is lost in one eye. In other relapses, however, there are more dramatic effects such as feeling fatigued and “wobbly”.

To be definite in saying that it was a relapse, there has to be an MRI scan with a gadolinium. This is just a contrast medium used for MRI scans. It is much more observable with viewing inflammation because it tends to be luminescent whenever a certain lesion is considered active. If the lesions are active, then it means that demyelization is still taking place. When this occurs, then it is, indeed, a true relapse, and not merely symptoms of past lesions.

True relapse

For a relapse to be considered true relapse, it has to occur for at least twenty-four hours. Mini-relapses can also take place, which are mainly comprised of quirky symptoms that do not usually last for more than a couple of minutes up to a few hours only. But mini-relapses are not true relapses.

True relapses take several weeks before they stop.

About the Author
By Anders Eriksson, proud owner of this top ranked web hosting reseller site: GVO Hosting

PostHeaderIcon Causes Of Multiple Sclerosis

The only way to keep up with the latest about Multiple Sclerosis is to constantly stay on the lookout for new information. If you read everything you find about Multiple Sclerosis, it won’t take long for you to become an influential authority.

Up to now, multiple sclerosis is still idiopathic. This means that, although research for its cause is currently and continuously being done, its definite cause still has not been discovered. However, a variety of probable causes has been found. It is through these probable causes that the medical diagnosis of multiple sclerosis can be established.

For starters, there is always the hereditary factor. The hereditary factor is present in almost all of the diseases. For instance, if a great great grandmother had multiple sclerosis, then there is a big chance that her descendants might have the disease as well.

Aside from heredity, the environment, according to researchers, also affects the pathogenesis of multiple sclerosis. An antigen or allergen commonly found in the environment could trigger a response from the body that later on leads to an immunocompromised system.

Multiple Sclerosis being an autoimmune disease

Research has it that multiple sclerosis is an autoimmune disease which means that the body’s personal immune system attacks its own cells. For reasons that are still unknown, the body’s immune cells show aggression towards and obliterate the myelin sheath that covers the neurons like an insulator inside the brain and the spinal cord.

This myelin sheath is responsible for the transmission and the prevention of unnecessary electrical activity that short circuits one cell from another cell. Once communication between the brain and the other parts of the body is disrupted, the transmission of sensations and control messages are not anymore normal. This pathophysiology is that of multiple sclerosis.

Plaques in multiple sclerosis

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The progression of the disease’s symptoms is correlated with the development of new plaques within the parts of the brain that simultaneously control the affected areas. These plaques are developed from the demyelinated areas, which are basically the tiny round areas of gray neuron that no longer has a white myelin covering.

What makes multiple sclerosis more complicated is that, the pattern of the appearance of the plaques has absolutely no pattern. This makes multiple sclerosis completely unpredictable.

Inflammation of the myelin sheath

Normal cells are covered by a sheath that acts as an insulator. This sheath is made up of adipose substances that are called myelin. Myelin is very helpful in the correct and appropriate transmission of nerve impulses. Once this sheath is damaged from too much inflammation, multiple sclerosis occurs.

WBC action

T cells, which are special subsets of white blood cells, are important in the development of multiple sclerosis. Normally, the T cells are able distinguish between self and non-self. However, with multiple sclerosis, the T cells become weak when it comes to recognizing and differentiating self and non-self. In fact, in most multiple sclerosis cases, these lymphocytes recognize the healthy cells of the central nervous system as foreign and harmful and attack.

There is a BBB or a blood-brain barrier that serves as a tight barrier between the blood and the brain. This barrier is made up of endothelial cells that completely line the walls of the blood vessels. Since the auto-reactive T cells start attacking healthy cells and trigger an inflammatory process, they tend to cross the BBB, when they are not at all supposed to. This breaks down the BBB, thus, leading to multiple sclerosis.

About the Author
By Anders Eriksson, now offering the best guide on movie downloads over at free movie downloads

PostHeaderIcon Multiple Sclerosis According To The Multiple Sclerosis Association Of America

Are you looking for some inside information on Multiple Sclerosis? Here’s an up-to-date report from Multiple Sclerosis experts who should know.

What is the MSAA?

The MSAA or the Multiple Sclerosis Association of America is a non-profit organization that has a national affectation. Its main mission is to develop the quality of life for those who have multiple sclerosis or MS. With the MSAA, there is a wide variety of programs that they could choose from. These programs, no matter how diverse and different they get, are very good in managing services for those with MS, including their corresponding families.

What is it?

According to the MSAA, MS is actually the most common neurological disorder that is usually found in those in their young adulthood stage of development. Since its causes have still not yet been identified completely, researchers never stop in looking for the answers to questions that have been asked ages ago.

MS is not at all contagious. It does not quicken a life expectancy for those who have sadly developed this disease. It is a known fact that nothing can cure this disease and that prevention is not as easy as it may sound. But still, there are many treatment methods that are very successful in reducing the disease’s severity and slowing the progression down to a minimum.

What does it affect?

Multiple sclerosis usually affects the CNS or the central nervous system. This is made up of the brain, nerves and the spinal cord. With MS, the myelin is damaged, leading to incorrect transmission of impulses and messages. The myelin is an insulator for the nerves as it surrounds them. This is then given the medical term of axon.

Most of this information comes straight from the Multiple Sclerosis pros. Careful reading to the end virtually guarantees that you’ll know what they know.

In short, once multiple sclerosis takes its toll, nerve impulses that are usually transmitted from the brain and the spinal cord short circuits. Afterwards the body reduces, if not totally loses, its normal functioning.

Duration of effects

The effects that occur with MS probably differ with each person. In others who have had the disease in only over a short period of time. After this short period, things might be symptom-free for some time.

Many believe that MS is an autoimmune disorder. Actually, according to research, it is definitely an autoimmune disease. The body’s white blood cells or the fighter cells become misguided and attack its own cells, ones that are healthy all throughout the body. Once there is inflammation within the person’s head, then further damage to the myelin must be avoided.

Areas of inflammation

Those areas that have inflamed are given the term of lesions or plaques. They vary in number, location and size and these lesions can determine the type of multiple sclerosis that is occurring and just how severe the symptoms are. It is such a misfortune that MS is usually clinically silent with no increase in terms of the disease’s symptoms. However, there are obvious demonstrations of abnormal activity within the person’s head.

Scar tissues may also result on the big areas of the damaged myelin. The term multiple sclerosis actually came from back then with regards to a hardened plaque. The word multiple is congruent in meaning with many while sclerosis means scarring.

Those who only know one or two facts about Multiple Sclerosis can be confused by misleading information. The best way to help those who are misled is to gently correct them with the truths you’re learning here.

About the Author
By Kenneth Allan Crosby jr,feel free to visit his top ranked recycling site: recycling, tips, history

PostHeaderIcon The Kurtzke Expanded Disability Status Scale And Multiple Sclerosis

What is this scale?

The Kurtzke Expanded Disability Status Scale, otherwise known as the EDSS, is a famous way of quantifying how much is already disabled in a person with multiple sclerosis. This tool replaced the Disability Status Scales which did as much as grouping people with multiple sclerosis.

The Kurtzke EDSS enumerates the disabilities associated with MS or multiple sclerosis according to the established eight functional systems. This then allows many neurologists to allocate a specific functional system score in each. The functional systems are as follows: pyramidal, cerebellar, brainstem, sensory, bowel and bladder, visual, cerebral, and others.

The Kurtzke EDSS gives two distinctive classifications to two different types of damage due to multiple sclerosis, depending on the severity of the disease’s symptoms. For instance, grades 1.0 up to 4.5 mean people who have multiple sclerosis but are fully ambulatory. On the other hand, those who are graded 5.0 up to 9.5 are those who are impaired in their ambulation.

Its discovery

Dr. Kurtzke established this useful scale back in August of 1955. The scale he discovered was initially called the DSS, which evaluated the impairment associated with MS based on a ten-point scale. And then it was in 1983 that Dr. Kurtzke discovered the EDSS. This latest tool became more famous and much more useful because it could evaluate MS-related impairment in all of the main neurological areas.

Even though the EDSS is not so sensitive when it comes to assessing temporary changes in the person’s level of consciousness, this tool is immensely utilized for not just national but also international tests in evaluating just how effective a certain therapy can be.

Think about what you’ve read so far. Does it reinforce what you already know about Multiple Sclerosis? Or was there something completely new? What about the remaining paragraphs?

The EDSS is predominantly built for assessing the person’s ambulation and not cognition, fatigue or the functioning of the upper extremities.

Its FS Scale

The FS scale or the functional systems scale is important to the EDSS since it assesses and evaluates the seven parts of the central nervous system which have the ability to control the normal functioning of the body. For instance, those who can function normally are graded 0 while those who are unable to finish the assignment are given the grade of 6.

The FS scale of the EDSS is important for those people with multiple sclerosis but can still ambulate since it evaluates where a certain person may have some disability or difficulty.

According to many research findings, the Kurtzke EDSS and a certain scale for the ADL’s or activities of daily living have a symbiotic relationship towards one another. Together, these two scales are able to assess the amount of disability that occurs in multiple domains of functioning, all depending on the person’s subjective report of any of the symptoms of multiple sclerosis.

Although the EDSS is the standard way of finally assessing the amount of disability and impairment, it is still greatly criticized for the putting far too much focus on the use of the lower extremities or the legs and not much attention to the general clinical change.

What are used?

In evaluating the disease status, MRI scans are used by the physicians. However, such diagnostic test is not so correlational with the outcome of the disease, since in multiple sclerosis, majority of the lesions are not seen via the MRI scan. Some even do not have symptoms that can be clinically detected.

Now that wasn’t hard at all, was it? And you’ve earned a wealth of knowledge, just from taking some time to study an expert’s word on Multiple Sclerosis.

About the Author
By Kenneth Allan Crosby jr,feel free to visit his top ranked recycling site: recycling, tips, history

PostHeaderIcon All About Multiple Sclerosis

What is it?

It has been scientifically determined that multiple sclerosis can potentially debilitate a person. This means that the body’s own immune system attacks the sheath that protects the nerves. Once this sheath is damaged or totally destroyed, the normal communication between the person’s brain and the rest of the body is interfered. This condition results into the deteriorating of the nerves, a complication that can never be reversed.

Its symptoms

The symptoms of multiple sclerosis may vary depending on how much damage has occurred to the nerves that are affected. Those who have the severe type of multiple sclerosis can end up being bedridden since their ability to walk or to talk is destroyed.

What is very bothersome about these symptoms is that they tend to come and go. This means that they could suddenly arrive and then suddenly disappear for a few months. This is why doctors find it initially difficult to diagnose multiple sclerosis during its early stages.

Multiple sclerosis symptoms are also usually manifested by people between the ages of twenty and forty. Although multiple sclerosis can happen to anyone from any age, this is the common age range that is affected. Also, according to statistical research, the women are the ones who usually carry this debilitating disorder.

There is numbness or fatigue in one limb or both. This kind of weakness usually occurs on just one side of the body at a single time. However, there have been reports that it could happen to the entire bottom part of the body. This condition is often accompanied with a tingling sensation that is sometimes painful in some parts of the body.

I trust that what you’ve read so far has been informative. The following section should go a long way toward clearing up any uncertainty that may remain.

There is also a partial or a complete visual loss which starts at one time then ends with having pain whenever both eyes move. This condition is given the medical term of optic neuritis. Apart from loss of vision, double vision or blurring of vision can also occur.

There could also be sensations like electrical shock that occur whenever the head is moved. Tremors also happen with the accompaniment of absence of coordination and imbalanced gait.

Many who have multiple sclerosis might experience relapses of the symptoms, especially during the early stages of the disorder. This relapsing phase is often followed by partial or complete remission.

Its causes

As minimally mentioned, multiple sclerosis is an autoimmune disease. This means that the body’s immune system attacks its own cells and tissues. The myelin, which is a protective wall that insulates the nerve fibers within, is damaged in multiple sclerosis. Once it is damaged, foreign substances that are potentially harmful can then freely destroy the open and unprotected nerve fibers.

Multiple sclerosis can happen to anyone from any age. However, it has been discovered that it usually occurs to people who are between twenty and forty years of age. As mentioned, women are also the ones who usually carry such disease. In fact, women are twice more likely to have multiple sclerosis than men.

As any other condition, heredity plays an important role. The risk of developing multiple sclerosis is greater for those who have a family history of the disease than for those who do not. If one of the parents has the disease, then there is a one to three percent possibility that multiple sclerosis may develop.

When it comes to identical twins, things are much more complicated and difficult to ascertain. Identical twins would mean having identical risks, according to some medical scientists. However, this is not the case because a twin who has multiple sclerosis only gives his or her identical twin a thirty percent possibility of having the very same disorder.

The day will come when you can use something you read about here to have a beneficial impact. Then you’ll be glad you took the time to learn more about Multiple Sclerosis.

About the Author
By Anders Eriksson, now offering the best guide on movie downloads over at free movie downloads